Table of Contents “...Eugenics and the racial genome: politics at the molecular level /...”

Table of Contents “...History and scope of epidemiology -- Practical applications of epidemiology -- Measures of morbidity and mortality -- Descriptive epidemiology : person, place, time -- Sources of data for use in epidemiology -- Study designs : ecologic, cross-sectional, case-control -- Study designs : cohort studies -- Experimental study designs -- Measures of effect -- Data interpretation issues -- Screening for disease in the community -- Epidemiology of infectious diseases -- Epidemiologic aspects of work and the environment -- Molecular and genetic epidemiology -- Social, behavioral, and psychosocial epidemiology -- Epidemiology as a profession....”

Subjects “...Cancer Molecular aspects....”

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Table of Contents “...Advances in clinical endpoints for neurocognitive rehabilitation in Down syndrome Jamie Edgin, Goffredina Spano and Lynne Nadel; Part II. Genetics, Brain and Animal Models: 4. New perspectives on molecular and genetic therapies in Down syndrome Jean-Maurice Delabar; 5. ...”

Table of Contents “...Freitag, W. Retz -- Molecular genetics of attention-deficit hyperactivity disorder / W. ...”

Table of Contents “...Parenting and family contextParental hostility; Coercive parent-child interactions; ODD in the school context; ODD and clinical issues; Informant effects; Assessment tools; Treatment; Conclusions; References; Further Reading; 3 Conduct disorder: a neurodevelopmental perspective; Historical context; Prevalence and overview of societal costs; Sex differences; Etiology as a multifactorial ontogenic process; Genetic vulnerabilities; Behavioral genetics; Molecular genetics; Linkage studies; Association studies; Genome-wide association studies; Structural variants; Epigenetics....”
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Table of Contents “....] -- Migrant studies / Song-Yi Park and Laurence N. Kolonel -- Molecular epidemiology studies in cancer / Kelly Hirko, Maria Iniesta Donate, Sofia Merajver -- Opportunities for cancer genetic research / Oluwafemi Oluwole, Yonglan Zheng, Olufunmilayo Olopade -- Cancer screening in low- and middle-income countries / R. ...”

Table of Contents “...Gray -- Cellular and molecular mechanics of aging of the vocal fold / Leslie T. ...”
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Table of Contents “...Scappaticci ; Inhibiting Cancer Angiogenesis With Molecular Therapy / Qixin Leng and A. James Mixson -- VI-B. ...”
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Table of Contents “...-- 1.2 Evidence suggests that cancer is a disease of the genome at cellular level -- 1.3 Influential factors in human carcinogenesis -- 1.4 Principles of conventional cancer therapies -- 1.5 Clinical trials -- 1.6 The role of molecular targets in cancer therapies -- 2 DNA structure and stability: mutations versus repair -- 2.1 Gene structure -- two parts of a gene : the regulatory region and the coding region -- 2.2 Mutations -- 2.3 Carcinogenic agents -- 2.4 DNA repair and predispositions to cancer -- Therapeutic strategies -- 2.5 Conventional therapies : chemotherapy and radiation therapy -- 2.6 Strategies that target DNS repair pathways -- 3 Regulation of gene expression -- 3.1 Transcription factors and transcriptional regulation -- 3.2 Chromatin structure -- 3.3 Epigenetic regulation of transcription -- 3.4 Evidence of a role for epigenetics in carcinogenesis -- 3.5 long non-coding RNAs -- 3.6 MicroRNAs (miRNAs) and regulation of mRNA expression -- 3.7 Telomeres and telomerase -- Therapeutic strategies -- 3.8 Epigenomic and histonomic drugs -- 3.9 Non-coding RNAs for diagnosis -- 3.10 Telomerase inhibitors -- 4 Growth factor signaling and oncogenes -- 4.1 Epidermal growth factors signaling: an important paradigm -- 4.2 Oncogenes -- Therapeutic strategies -- 4.3 Kinases as drug targets -- 5 The cell cycle -- 5.1 Cyclins and cyclin-dependent kinases (cdks) -- 5.2 Mechanisms of cdk regulation -- 5.3 Progression through the G1 checkpoint -- 5.4 The G2 checkpoint -- 5.5 The mitotic checkpoint -- 5.6 The cell cycle and cancer -- Therapeutic cancer -- 5.7 Cyclin-dependent kinase inhibitors -- 5.8 Other cell cycle kinase targets -- 5.9 Inhibitors of the mitotic spindle -- 6 Growth inhibitor and tumor suppressor genes -- 6.1 Definitions of tumor suppressor genes -- 6.2 The retinoblastoma gene -- 6.3 Mutations in the RB pathway and cancer -- 6.4 The p53 pathway -- 6.5 Mutations in the p53 pathway and cancer -- 6.6 Interaction of DNA viral protein products with RB and p53 -- Therapeutic strategies -- 6.7 Targeting of the p53 pathway -- 7 Apoptosis -- 7.1 Molecular mechanisms of apoptosis -- 7.2 Apoptosis and cancer -- 7.3 Apoptosis and chemotherapy -- 7.4 Apoptotic drugs -- 8 Cancer stem cells and the regulation of self-renewal and differentiation pathways : focus on colon cancer and leukemias -- 8.1 Cancer stem cells -- 8.2 The regulation of differentiation by gene expression -- Therapeutic strategies -- 8.3 Inhibitors of the Wnt pathway -- 8.4 Inhibitors of the Hh pathway -- 8.5 Inhibitors of PcG proteins -- 8.6 Leukemia and differentiation therapies -- 9 Metastasis -- 9.1 How do tumors spread? ...”

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Table of Contents “...Robert Horsburgh, Jr., and Barbara E. Mahon -- Genetic and molecular epidemiology / Muin J. Khoury, Robert Millikan, and Marta Gwinn -- Nutritional epidemiology / Walter C. ...”
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Table of Contents “...Widiger -- Construct validity -- Behavior and molecular genetics of personality disorders / Susan C. ...”

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