Human molecular genetics / Tom Strachan, Andrew P. Read.
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| Edition: | Fifth edition. |
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| Published: |
Boca Raton, Florida :
CRC Press, Taylor & Francis Group
[2019]
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| Main Author: | |
| Other Authors: | |
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| Format: | Book |
Table of Contents:
- Pt. 1: Basics of DNA, chromosomes, cells, development and inheritance
- Basic principles of nucleic acid structure and gene expression
- Fundamentals of cells and chromosomes
- Fundamentals of cell-cell interactions and immune system biology
- Aspects of early mammalian development, cell differentiation, and stem cells
- Patterns of inheritance
- Pt. 2: Understanding genomes
- Core DNA technologies: amplifying DNA, nucleic acid hybridization, and DNA sequencing
- Analyzing the structure and expression of genes and genomes
- Principles of genetic manipulation of mammalian cells
- Uncovering the architecture and workings of the human genome
- Gene regulation and the epigenome
- Pt. 3: Genetic variation between individuals and species
- An overview of human genetic variation
- Human population genetics
- Comparative genomics and genome evolution
- Human evolution
- Pt. 4: Human genetic disease
- Chromosomal abnormalities and structural variants
- Moleculars pathology: connecting phenotypes to genotypes
- Mapping and identifying genes for monogenic disorders
- Complex disease identifying susceptibility factors and understanding pathogenesis
- Cancer genetics and genomics
- Pt. 5: Applied human molecular genetics
- Genetic testing in healthcare and the law
- Model organisms and modeling disease
- Genetic approaches to treating disease.
